Duchenne muscular dystrophy (DMD) is caused by a lack of dystrophin.1,2
In DMD, a gene change (mutation) prevents the body from producing enough dystrophin.1–3 Dystrophin acts as a shock absorber or stabiliser for muscles.4
If the body does not have enough dystrophin, muscle cells become more sensitive to damage and deteriorate over time.3
The injured muscles are gradually replaced with fat and scar tissue.3,5
The lack of dystrophin and resulting loss of muscle lead to the symptoms of DMD.1,2
(excluding UK and Ireland)
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